Virginia Ann Appleberry was born in 1824 in Virginia. She married Columbus Jackson in Prairieville, Missouri in 1848. Her husband, Columbus, spent most of his life in Fayetteville, Arkansas, engaged in the mercantile business. During the War Between the States, many widows and orphans came to him not only for advice but for assistance. While serving in the Confederate Army his health suffered and he never enjoyed good health after the war. He and Virginia bought and improved a farm about 1.5 miles from the old Post Office and built a 2-story brick home there. Virginia lived to be almost 89 years old and Columbus died in 1879.
Virginia's husband, Columbus Jackson, was born 20 January 1825 in Kentucky and died 25 September 1879. He was the second son of Julius C. Jackson, who was a second cousin to Confederate General Thomas J. Jackson. Columbus Jackson was noted for his good business qualities and his unvarying cheerfulness. He and his family helped largely to make Fayetteville one of the best in the state. His mother returning from a visit to Fayetteville, once commented that, "everyone seemed to know and respect Columbus. He seemed to have the confidence and love of all classes, especially of those who needed the counsel of an honest, wise man."
Columbus and his wife Virginia produced nine children: William Julius, born and died in 1849; Lyses born in 1850, died in 1853; Everett A. born in 1852, Wayman Crow born in 1855, Ulysses L. born in 1858, Mary Frances, born in 1862, died in 1863; Lynn, born in 1862 died in 1863; Virginia Alice, born in 1867, Henry Rush, born in 1869.